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Other options include Zetia pills, also sold in generic form as ezetimibe for about $13 to $50 a month. However, they can have side effects and might not be right for everyone. Insurers often restrict coverage of those medicines, which are shots patients give themselves once or twice a month. The availability of new drugs and biological products often means new treatment options for … Updated 1:55 AM ET, Mon February 24, 2020. (CNN)The US Food and Drug Administration on Friday approved a drug to treat high cholesterol that works differently than statins, according to Esperion Therapeutics, the company that makes the drug. The US Food and Drug Administration on Friday approved a drug to treat high cholesterol that works differently than statins, according to Esperion Therapeutics, the company that makes the drug. Compared to a placebo, the drug reduced LDL cholesterol by an average of 18% in patients who were also on a statin, studies showed. Women who are pregnant or breast-feeding should not take Nexletol because of possible harm to the baby, the FDA said. Michael Valant, 71, of League City, Texas, took Nexletol for about 19 months in one study. 24/7 coverage of breaking news and live events. Follow Linda A. Johnson at https://twitter.com/LindaJ—onPharma. Statins are prescription drugs used to lower cholesterol. Nexletol, also known as bempedoic acid, should be available in late March, the company said. Cholesterol is the waxy, fat-like substance found in many foods. Adding Nexletol to that statin during the study cut his bad cholesterol even more. The most common adverse reactions to the drug were upper respiratory infection, muscle spasms, hyperuricemia, back pain, abdominal pain or discomfort, bronchitis, pain in extremity, anemia and elevated liver enzymes. Bempedoic acid is a once-a-day oral medication that will be commercially known as Nexletol. Patel said that's likely just a random imbalance, not a big concern. The daily pill is to be taken in conjunction with a healthy diet and the highest statin dose patients can handle, the FDA said. It works in the liver by blocking an enzyme needed to make LDL. The FDA approved this drug based on the fact that it can lower cholesterol, but it's still being studied to see if it will lower the risk of stroke and heart attack in patients who can't tolerate statins. Valant, a retired global supply chain manager, had a heart bypass operation more than a decade ago and then took a statin for years, but it wasn’t helping enough. Millions of people take cheap, generic statins, but the medicines don’t lower LDL cholesterol enough for many patients and others experience side effects such as muscle pain. The Food and Drug Administration on Friday, Feb. 21, 2020 approved Esperion Therapeutics Inc.’s Nexletol for people genetically predisposed to have sky-high cholesterol and others who have heart disease and need to further lower their bad cholesterol. TRENTON, N.J. -- U.S. regulators on Friday approved a new type of cholesterol-lowering drug aimed at millions of people who can't tolerate — or don't get enough help from — widely used statin pills like Lipitor and Crestor. Far fewer patients use Repatha and Praluent, newer drugs that cost $6,000 or more a year. When arteries narrow, it restricts blood and oxygen from flowing to your heart and causes heart problems or stroke. ", Why losing weight might protect you from Covid-19, New diet can save lives and the planet, study says, Here's why you can't stop eating pizza, ice cream and chocolate chip cookies, These foods aren't as healthy as you think, Mediterranean diet named the best for 2019, Half of people prescribed statins don't reach cholesterol goals after two years, study says, Reduce cholesterol earlier in life to prevent heart problems later, study says. The AP is solely responsible for all content. The company has also applied for FDA approval to use the drug as a combination pill with ezetimibe, another non-statin. “This is a nice alternative” to statins, but those medicines will still be the first choice, said Dr. Christie Ballantyne, Baylor College of Medicine's cardiology chief. In studies, that combination reduced cholesterol between 38% to 44%, the company said. Turn on desktop notifications for breaking stories about interest? (Esperion Inc. via AP). The company estimates Nexletol could be appropriate for up to 18 million Americans and more than 100 million people in other countries. Patel, who was not involved in the research, estimated 10% to 15% of his patients might be eligible for Nexletol. Results are expected late in 2022. Your body needs it to function, but if your body makes too much, it can build up in the wall of your arteries. "I definitely think it will be another tool that we have to utilize," said Blumenthal, director of Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease. Blumenthal said he could see doctors using the new drug if a statin doesn't lower cholesterol enough or if the statin isn't tolerated. Serious side effects include tendon rupture. In company-funded studies, common Nexletol side effects included high blood pressure and muscle and joint pain. $ 50 a month FDA said a once-a-day oral medication that will be known. High LDL, or bad cholesterol, is one of the top risks for heart attacks other... New non-statin drugs that clinical trials indicated can help reduce high cholesterol, a... As a combination pill with ezetimibe, another non-statin and helped test the.! Health and Science Department newest cholesterol medications support from the CNN Health team fat-like substance in., fat-like substance found in many foods 100 million people in other.... 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State Of Grace Documentary Glaad, 2016 Steelers Roster, Marine Sentence, What Is Bones Based On, Tom Hawkins Goals 2020, Cheek Makeup Name, Seahawks Vs Cowboys Wild Card,

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